4-Methylbenzamide oxime

4-Methylbenzamide oxime
  • CAS No.:19227-13-5

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
4-Methylbenzamide oxime Basic information
Product Name:4-Methylbenzamide oxime
Synonyms:N-HYDROXY-4-METHYL-BENZAMIDINE;N'-HYDROXY-4-METHYLBENZENECARBOXIMIDAMIDE;P-TOLUAMIDEOXIME;n-hydroxy-4-methyl-benzenecarboximidamid;4-Methylbenzamidoxime 97%;p-tolamidoxime;p-toluamidoxime;BUTTPARK 33\11-54
CAS:19227-13-5
MF:C8H10N2O
MW:150.18
EINECS:
Product Categories:OXIME;pharmacetical
Mol File:19227-13-5.mol
4-Methylbenzamide oxime Chemical Properties
Melting point 140-145 °C (lit.)
Boiling point 258.1±33.0 °C(Predicted)
density 1.14±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka6.95±0.69(Predicted)
CAS DataBase Reference19227-13-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS XS4870000
HazardClass IRRITANT
HS Code 2928009090
MSDS Information
ProviderLanguage
SigmaAldrich English
4-Methylbenzamide oxime Usage And Synthesis
Description4-Methylbenzamide oxime is intended to be used as a building block in drug discovery chemistry.
UsesN-Hydroxy-4-methyl-benzenecarboximidamide is a reactant used in the preparation of naphthyridine-based polycyclic hetarenes from N-hydroxybenzamidines and alkynes.
General Description4-Methylbenzamide oxime is a benzonitrile derivative that can be prepared from 4-methylbenzonitrile and hydroxylamine hydrochloride. Its crystalline structure shows the presence of both intramolecular and intermolecular hydrogen bonds. 3-Aryl-5-trinitromethyl-1,2,4-oxadiazoles undergoes hydrolysis under acidic conditions to form 4-methylbenzamide oxime as one of the product.
4-Methylbenzamide oxime Preparation Products And Raw materials
Raw materialsP-TOLUAMIDE-->Phenol-->Methanol-->Acetonitrile-->Dimethyl carbonate-->Triethylamine-->p-Tolunitrile-->p-Tolualdehyde
Preparation Products4-Nitrophenol

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