| AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE Basic information |
| Product Name: | AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE |
| Synonyms: | (4S)-4-Amino-4-carboxybutanehydroxamic acid;(S)-4-Amino-4-carboxybutanehydroximic acid;3-[2-Oxo-2-(hydroxyamino)ethyl]alanine;L-Glutamic acid γ-hydroxamate;N5-Hydroxy-L-glutamine;(2S)-5-amino-2-(hydroxyamino)-5-keto-valeric acid;(2S)-5-amino-2-(hydroxyamino)-5-oxopentanoic acid;(2S)-5-azanyl-2-(hydroxyamino)-5-oxo-pentanoic acid |
| CAS: | 1955-67-5 |
| MF: | C5H10N2O4 |
| MW: | 162.14 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 1955-67-5.mol |
| AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE Chemical Properties |
| Melting point | 154 °C |
| density | 1.432±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| pka | 2.21±0.10(Predicted) |
| Safety Information |
| WGK Germany | 3 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE Usage And Synthesis |
| Uses | L-Glutamic acid γ-monohydroxamate has been used as a standard to calculate transglutaminase (TGase) activity. |
| Definition | ChEBI: A hydroxamic acid that is L-glutamine hydroxylated at N-5. |
| Biochem/physiol Actions | L-Glutamic acid γ-monohydroxamate [L-Glu(gamma)HXM] is used as a vanadium ligand which potentiates vanadiums metabolic activity. L-Glu(gamma)HXM is also used as a substrate for E. coli asparagine synthetase B and as an ATP-dependent irreversible inhibitor of Escherichia coli gamma-glutamylcysteine synthetase. |
| AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE Preparation Products And Raw materials |
| Raw materials | H-GAMMA-GLU-GLN-OH-->N-γ-L-glutamyl-4-aminobutyric acid-->H-GLU(OET)-OH-->L-(+)Sodium glutamate-->L-Glutamic acid-->L-Glutamine-->Glutathione-->4-Aminobutyric acid |
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