4,4'-BIS(BROMOMETHYL)BIPHENYL

CAS No.：20248-86-6

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
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4,4'-BIS(BROMOMETHYL)BIPHENYL Basic information

Product Name:	4,4'-BIS(BROMOMETHYL)BIPHENYL
Synonyms:	4,4'-BIS(BROMOMETHYL)BIPHENYL;4,4''-BIS(BROMOMETHYL)BIPHENYL 98%;Bisbromomethylbiphenyl;1-(bromomethyl)-4-[4-(bromomethyl)phenyl]benzene;α,α′-Dibromo-p,p′-bitolyl;4,4'-Bis(bromomethyl)biphenyl >=97.0% (HPLC);4,4'-Bis(broMoMethyl)-1,1'-biphenyl;4,4'-Bis(bromomethyl
CAS:	20248-86-6
MF:	C14H12Br2
MW:	340.05
EINECS:
Product Categories:	Biphenyl & Diphenyl ether;Biphenyls (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research
Mol File:	20248-86-6.mol

4,4'-BIS(BROMOMETHYL)BIPHENYL Chemical Properties

Melting point	169.0 to 173.0 °C
Boiling point	399.8±37.0 °C(Predicted)
density	1.591±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Acetonitrile (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly)
form	Solid
color	White to Off-White
BRN	2444585
CAS DataBase Reference	20248-86-6

Safety Information

Hazard Codes	C,N
Risk Statements	36/37/38-50/53-34-22
Safety Statements	26-36/37/39-61-60-45
RIDADR	UN 3261 8 / PGIII
WGK Germany	3
HazardClass	8
PackingGroup	III
HS Code	29039990

MSDS Information

4,4'-BIS(BROMOMETHYL)BIPHENYL Usage And Synthesis

Chemical Properties	Off-white powder
Uses	4,4''-Bis(bromomethyl)-1,1''-biphenyl is a genotoxic impurity from valsartan antihypertensive drug.

4,4'-BIS(BROMOMETHYL)BIPHENYL Preparation Products And Raw materials

Raw materials	Hydrogen bromide-->Phosphoric acid-->Paraformaldehyde-->Biphenyl
Preparation Products	4,4'-biphenyldiacetonitrile-->4,4'-Bis(hydroxymethyl)biphenyl

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