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| 2-AMINO-2-NORBORNANECARBOXYLIC ACID Basic information |
| Product Name: | 2-AMINO-2-NORBORNANECARBOXYLIC ACID | | Synonyms: | 2-AMINO-2-NORBORNANECARBOXYLIC ACID;2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID;BCH;2-AMINO-2-NORBORNANECARBOXYLIC ACID, 98% , MIXTURE OF ISOMERS;2-Amino-2-carboxy-bicyclo-2,2,1-heptane;2-Aminonorbornane-2-carboxylic acid;B-Bch;Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-amino- | | CAS: | 20448-79-7 | | MF: | C8H13NO2 | | MW: | 155.19 | | EINECS: | | Product Categories: | | Mol File: | 20448-79-7.mol |
| 2-AMINO-2-NORBORNANECARBOXYLIC ACID Chemical Properties |
| Melting point | >300 °C(lit.) | | Boiling point | 295.5±23.0 °C(Predicted) | | density | 1.256±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Aqueous Acid (Slightly) | | form | Solid | | pka | 2.58±0.20(Predicted) | | color | White | | CAS DataBase Reference | 20448-79-7(CAS DataBase Reference) |
| 2-AMINO-2-NORBORNANECARBOXYLIC ACID Usage And Synthesis |
| Uses | 2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells | | General Description | 2-Amino-2-norbornanecarboxylic acid is a potential large amino acid transporters inhibitor. It may suppress tumor progression and apoptosis. | | Biochem/physiol Actions | 2-Amino-2-norbornanecarboxylic acid (BCH) is a Na(+)-independent system L specific substrate used with other system specific substrates such as the system A specific substrate α-(methylamino) isobutyric acid and system N specific substrate L-glutamic acid gamma-monohydroxamate to help identify, differentiate and characterize amino acid transport systems in cells. |
| 2-AMINO-2-NORBORNANECARBOXYLIC ACID Preparation Products And Raw materials |
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