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| 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& Basic information |
| Product Name: | 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& | | Synonyms: | 4,4''-DIISOTHIOCYANATOSTILBENE-2,2''-DISULPHONIC ACID DISODIUM SALT;4,4μ-Diisothiocyanato-2,2μ-stilbenedisulfonic acid hydrate disodium salt;4,4μ-Diisothiocyanatostilbene-2,2μ-disulfonic acid hydrate disodium salt;DIDS, Disodium 4,4μ-diisothiocyanatostilbene-2,2μ-disulfonate;4,4'-Diisothiocyanatostilbene-2,2'-disulphonic acid disodium salt hydrate;Disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulphonate hydrate;DisodiuM 4,4'-diisothiocyanatostilbene-2,2'-disulfonate, 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodiuM salt hydrate;Disodium 4,4′-diisothiocyanatostilbene-2,2′-disulfonate | | CAS: | 207233-90-7 | | MF: | C16H8N2O6S4.2Na | | MW: | 498.491 | | EINECS: | | Product Categories: | homoXlink | | Mol File: | 207233-90-7.mol |
| 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& Chemical Properties |
| storage temp. | 2-8°C | | solubility | 0.1 M potassium bicarbonate: soluble50mg/mL | | form | powder | | color | yellow | | BRN | 8179433 |
| Hazard Codes | Xn | | Risk Statements | 36/37/38-42 | | Safety Statements | 22-26 | | WGK Germany | 3 | | HS Code | 29309090 |
| 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& Usage And Synthesis |
| Uses | 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate has been used:- as band3 protein inhibitor in rabbits(19)
- for the inhibition of bicarbonate transporters in brain slice tissue(20)
- as HCO3-/Cl- exchanger (anion exchanger) in embryos(21)
| | Biochem/physiol Actions | 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is an anionic alkylating agent containing isothiocyanate residue. It is a negatively charged homobifunctional cross-linking reagent. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is a specific inhibitor of cellular anion permeability used in cell transport studies. The isothiocyanate groups react with primary amines at pH 9.0-10.0. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid alkylates lysine residues and inhibits apoptosis indirectly by targeting membrane based anion transporters.In addition, it also inhibits calcium transport in vesicles. |
| 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& Preparation Products And Raw materials |
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