D-PENICILLAMINE DISULFIDE

CAS No.：20902-45-8

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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D-PENICILLAMINE DISULFIDE Basic information

Product Name:	D-PENICILLAMINE DISULFIDE
Synonyms:	NSC 87505;3,3'-DITHIOBIS(2-AMINO-3-METHYLBUTYRIC ACID);3,3''-Dithiobis-D-valine;D-Penicillamine disulfide,3,3′-Dithiobis(2-amino-3-methylbutanoic acid), S,S′-Bi(D-penicillamine);D-Penicillamine disulfide,3,3′-Dithiobis(2-amino-3-methylbutanoic acid), 3,3′-Dithiobis(2-amino-3-methylbutyric acid), S,S′-Bi(D-penicillamine);Penicillamine Disulfide (200 mg);Penicillamine Disulfide (100 mg);Penicillamine Disulde (100 mg)
CAS:	20902-45-8
MF:	C10H20N2O4S2
MW:	296.41
EINECS:	244-107-2
Product Categories:
Mol File:	20902-45-8.mol

D-PENICILLAMINE DISULFIDE Chemical Properties

Melting point	204 °C (dec.)(lit.)
alpha	D23 +27° (c = 1.46 in 1N HCl)
Boiling point	467.0±45.0 °C(Predicted)
density	1.353±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Aqueous Base (Slightly), Water (Slightly)
pka	1.76±0.12(Predicted)
form	neat
color	White to Off-White
optical activity	[α]25/D 75°, c = 1 in 1 M NaOH
Merck	13,7161
BRN	4461521
Stability:	Hygroscopic

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	2930904915

MSDS Information

Provider	Language
SigmaAldrich	English

D-PENICILLAMINE DISULFIDE Usage And Synthesis

Uses	D-Penicillamine Disulfide is used in the treatment of neurodegenerative diseases such as Parkinson’s and Motor Neuron Disease. Inactivator of α1-antiproteinase, preventing deleterious effects of peroxynitrite.
Definition	ChEBI: An organic disulfide consisting of two D-penicillamines joined by a disulfide bond.

D-PENICILLAMINE DISULFIDE Preparation Products And Raw materials

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