MONASCIN

MONASCIN
  • CAS No.:21516-68-7
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MONASCIN Basic information
Product Name:MONASCIN
Synonyms:MONASCIN;(3S)-3aα,4,8,9a-Tetrahydro-9aβ-methyl-3-(1-oxohexyl)-6-[(E)-1-propenyl]-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione;Monascoflavin;Ccris 9138;(3S,3aR,9aR)-3a,4,8,9a-Tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione;(3S,3aR,9aR)-3-Hexanoyl-9a-methyl-6-((E)-propenyl)-3a,4,8,9a-tetrahydro-3H-furo[3,2-g]isochromene-2,9-dione;2H-Furo[3,2-g][2]benzopyran-2,9(3H)-dione, 3a,4,8,9a-tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propen-1-yl-, (3S,3aR,9aR)-;Monascin >=97.0% (HPLC)
CAS:21516-68-7
MF:C21H26O5
MW:358.43
EINECS:
Product Categories:
Mol File:21516-68-7.mol
MONASCIN Chemical Properties
Melting point 145 °C
Boiling point 574.6±50.0 °C(Predicted)
density 1.18±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka10.59±0.60(Predicted)
BRN 51355
InChIKeyXXKNHBAFFJINCK-RVEJDSBJSA-N
Safety Information
WGK Germany 2
MSDS Information
MONASCIN Usage And Synthesis
UsesMonascin is an azaphilonoid pigment extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration.
DefinitionChEBI: An organic heterotricyclic compound that is 3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione that is substituted at positions 3, 6, and 9a by hexanoyl, (1E)-prop-1-en-1-yl an methyl groups, respectively (the 3S,3aR,9aR diastereoisomer). One of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mould rice), it is a potent inhibitor of car inogenesis measured against chemical- or UV-initiated, phorbol-promoted mouse skin tumours.
Biochem/physiol ActionsMonascin is one of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mold rice). It is a potent inhibitor of carcinogenesis measured against chemical or UV initiated, phorbol-promoted mouse skin tumors.
MONASCIN Preparation Products And Raw materials

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