SB 277011 Hydrochloride

SB 277011 Hydrochloride
  • CAS No.:215804-67-4
Other grades of this product :
SB 277011 Hydrochloride Basic information
Product Name:SB 277011 Hydrochloride
Synonyms:SB 277011 Hydrochloride;N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- 4-quinolinecarboxaMide Hydrochloride;SB 277011A Hydrochloride;SB 277211 Hydrochloride;SB-277011-A hydrochloride hydrate
CAS:215804-67-4
MF:C28H30N4O
MW:438.564
EINECS:
Product Categories:Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:215804-67-4.mol
SB 277011 Hydrochloride Chemical Properties
storage temp. 2-8°C
solubility DMSO: soluble2mg/mL, clear (warmed)
form powder
color white to beige
Safety Information
WGK Germany 3
MSDS Information
SB 277011 Hydrochloride Usage And Synthesis
UsesA potent and selective dopamine D3 receptor antagonist.
UsesSB 277011 Hydrochloride is a potent and selective brain-penetrant D3 dopamine receptor antagonist (1,2,3).
Biochem/physiol ActionsThe D3 dopamine receptor antagonist, SB-277011-A inhibits the cocaine-seeking behavior and cocaine-enhances brain stimulation reward in in rats. It decreases drug-seeking behavior and may be useful in treatment of cocaine and methamphetamine addiction.
SB 277011 Hydrochloride Preparation Products And Raw materials

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