(S)-(-)-2-Hydroxy-3,3-dimethylbutyric acid

CAS No.：21641-92-9

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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(S)-(-)-2-Hydroxy-3,3-dimethylbutyric acid Basic information

Product Name:	(S)-(-)-2-Hydroxy-3,3-dimethylbutyric acid
Synonyms:	(S)-(-)-2-HYDROXY-3,3-DIMETHYLBUTYRIC ACID;(S)-(-)-2-HYDROXY-TERT-BUTYLACETIC ACID;(2S)-2-Hydroxy-3,3-dimethylbutyric acid;(S)-2-Hydroxy-3,3-dimethylbutanoic acid;(S)-(-)-2-Hydroxy-3,3-dimethylbutyric acid 97%;(2S)-2-Hydroxy-3,3-dimethylbutanoic acid;Butanoic acid, 2-hydroxy-3,3-dimethyl-, (2S)-
CAS:	21641-92-9
MF:	C6H12O3
MW:	132.16
EINECS:
Product Categories:	Carboxylic Acids;Chiral Building Blocks;Organic Building Blocks
Mol File:	21641-92-9.mol

(S)-(-)-2-Hydroxy-3,3-dimethylbutyric acid Chemical Properties

Melting point	48-50 °C (lit.)
alpha	-62 º (C=1 IN H2O)
Boiling point	242.4±13.0 °C(Predicted)
density	1.100±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	3.91±0.27(Predicted)
optical activity	[α]20/D 64±5°, c = 1 in H2O/molybdate

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	29181998

MSDS Information

Provider	Language
SigmaAldrich	English

(S)-(-)-2-Hydroxy-3,3-dimethylbutyric acid Usage And Synthesis

Uses	Building block for chiral tert-butyl substituted α-lactams, diols, and α-hydroxyketones.

(S)-(-)-2-Hydroxy-3,3-dimethylbutyric acid Preparation Products And Raw materials

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