Other grades of this product :
| 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Basic information |
| Product Name: | 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE | | Synonyms: | 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE;C75;C75(4-Methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylicacid);TRANS-4-CARBOXY-5-OCTYL-3-METHYLENEBUTYROLACTONE;TRANS-TETRAHYDRO-3-METHYLENE-2-OXO-5-N-OCTYL-4-FURANCARBOXYLIC ACID;FAS inhibitor C75
(C-75;3-Furancarboxylic acid, tetrahydro-4-methylene-2-octyl-5-oxo-;C75 >=98% (HPLC), powder | | CAS: | 218137-86-1 | | MF: | C14H22O4 | | MW: | 254.32 | | EINECS: | | Product Categories: | | Mol File: | 218137-86-1.mol |
| 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Chemical Properties |
| Boiling point | 432.1±45.0 °C(Predicted) | | density | 1.08±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: 18 mg/mL | | form | solid | | pka | 3.08±0.40(Predicted) | | color | off-white |
| 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Usage And Synthesis |
| Uses | C75 has been used:- as a fatty acid synthase (FASN) inhibitor to test its ability in the direct inhibition of FASN to attenuate mammosphere formation as compared to metformin
- as a pharmacological inhibitor to inhibit fatty acid synthesis in glioma stem cells (GSCs)
- as FASinhibitorin the pre-treatment of Chang cells to inhibit lipogenesis and reverse the senescence induced by hydrogen peroxide
| | Biochem/physiol Actions | C75 helps to increase the cancer‐killing capability of ionizing radiation. |
| 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Preparation Products And Raw materials |
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