ETHYNYL P-TOLYL SULFONE

ETHYNYL P-TOLYL SULFONE
  • CAS No.:13894-21-8

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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ETHYNYL P-TOLYL SULFONE Basic information
Product Name:ETHYNYL P-TOLYL SULFONE
Synonyms:1-(ethynylsulfonyl)-4-Methylbenzene;Ethynyl p-Tolyl Sulfone;ETHYNYL P-TOLYL SULFONE;P-TOLUENESULFONYLACETYLENE;TOSYLACETYLENE;p-Toluenesulfonylacetylene, Tosylacetylene;p-tolylsulfonylacetylene;Ethynylp-TolylSulfone&gt
CAS:13894-21-8
MF:C9H8O2S
MW:180.22
EINECS:
Product Categories:Acetylenes;Functionalized Acetylenes;Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry
Mol File:13894-21-8.mol
ETHYNYL P-TOLYL SULFONE Chemical Properties
Melting point 73-74 °C (lit.)
storage temp. Inert atmosphere,Room Temperature
solubility organic solvents: soluble(lit.)
form powder to crystal
color White to Light yellow
BRN 2556169
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29041000
MSDS Information
ProviderLanguage
SigmaAldrich English
ETHYNYL P-TOLYL SULFONE Usage And Synthesis
UsesEthynyl p-tolyl sulfone (Tosylacetylene) may be used in the synthesis of 2-(4-methylphenylsulfonyl)ethenyl (tosvinyl, Tsv) protected derivatives. It may be used as starting reagent for the synthesis of optically active indan-2-ols.
Synthesis Reference(s)The Journal of Organic Chemistry, 57, p. 697, 1992 DOI: 10.1021/jo00028a053
Purification MethodsRecrystallise the sulfone from pet ether, *C6H6 or EtOH (m 66o), and dry it in a vacuum. [Beilstein 6 III 1397, 6 IV 2160.]
ETHYNYL P-TOLYL SULFONE Preparation Products And Raw materials
Preparation ProductsBAY 11-7082

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