dl-3-hydroxynorvaline

dl-3-hydroxynorvaline
  • CAS No.:2280-42-4

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
dl-3-hydroxynorvaline Basic information
Product Name:dl-3-hydroxynorvaline
Synonyms:α-amino-β-hydroxyvaleric acid;α-Amino-β-hydroxyvaleric acid, 2-Amino-3-hydroxypentanoic acid, 3-Hydroxy-2-aminopentanoic acid, DL-β-Hydroxynorvaline;2-amino-3-hydroxy-valeric acid;2-azanyl-3-hydroxy-pentanoic acid;3-Hydroxy-DL-norvaline;beta-Hydroxynorvaline;DL-2-Amino-3-hydroxyvaleric acid;Norvaline, 3-hydroxy-
CAS:2280-42-4
MF:C5H11NO3
MW:133.15
EINECS:
Product Categories:
Mol File:2280-42-4.mol
dl-3-hydroxynorvaline Chemical Properties
Melting point 231.2℃
Boiling point 328.4±32.0 °C(Predicted)
density 1.237±0.06 g/cm3(Predicted)
storage temp. -20°C
pka2.39±0.24(Predicted)
BRN 1722350
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
dl-3-hydroxynorvaline Usage And Synthesis
DefinitionChEBI: A non-proteinogenic amino-acid derivative that is norvaline (2-aminopentanoic acid) in which a hydrogen at position 3 is replaced by a hydroxy group.
Biochem/physiol Actions3-Hydroxynorvaline (HNV) is a microbial, α amino acid threonine analogue which has antiviral activity (herpes virus) and is toxic to mammalian cells (embryotoxic and teratogenic) presumably via incorporation into proteins. 3-Hydroxynorvaline may be used as an unnatural amino acid to study the fidelity of protein translation at the level of acyl-tRNA editing. 3-Hydroxynorvaline may also be used to study enzymes and molecules involved in threonine metabolism.
dl-3-hydroxynorvaline Preparation Products And Raw materials

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