Fluorinated VHL Spy Molecule 4

CAS No.：2290526-31-5

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Fluorinated VHL Spy Molecule 4 Basic information

Product Name:	Fluorinated VHL Spy Molecule 4
Synonyms:	Fluorinated VHL Spy Molecule 4
CAS:	2290526-31-5
MF:	C15H16BrF3N2O3
MW:	409.2
EINECS:
Product Categories:
Mol File:	2290526-31-5.mol

Fluorinated VHL Spy Molecule 4 Chemical Properties

Safety Information

MSDS Information

Fluorinated VHL Spy Molecule 4 Usage And Synthesis

Uses

Fluorinated VHL Spy Molecule 4 can be used for the discovery of new von Hippel-Lindau (VHL) binders. Based on VH032 (cat# 901490), this reporter was designed in the lab of Alessio Ciulli to bind the hydroxyproline (Hyp) recognition site of VHL. When used in competition ligand-observed 19F NMR screening experiments, its displacement indicates binding by another molecule. Additional Fluorinated VHL Spy Molecules are available as listings 909416, 909432, and 909440.The E3 ligase VHL is of growing interest for targeted protein degradation, and these spy molecules will facilitate the identification of novel VHL ligands and VHL-based degraders.

Fluorinated VHL Spy Molecule 4 Preparation Products And Raw materials

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