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| 6alpha-Methylprednisolone sodium succinate Basic information |
| Product Name: | 6alpha-Methylprednisolone sodium succinate | | Synonyms: | (6alpha,11beta)-21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-pregna-1,4-diene-3,20-dione monosodium salt;6ALPHA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 21-HEMISUCCINATE SODIUM SALT;6ALPHA-METHYLPREDNISOLONE 21-HEMISUCCINATE SODIUM SALT;6-ALPHA-METHYLPREDNISOLONE SODIUM SUCCINATE;1,4-PREGNADIEN-6-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-SUCCINATE, SODIUM SALT;6α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate;6α-methylprednisolone 21-hemisuccinate sodium salt;Methylprednisolone sodium succinate (JAN/USP) | | CAS: | 2375-03-3 | | MF: | C26H33O8.Na | | MW: | 496.53 | | EINECS: | 219-156-8 | | Product Categories: | | Mol File: | 2375-03-3.mol |
| 6alpha-Methylprednisolone sodium succinate Chemical Properties |
| Melting point | >186°C (dec.) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | lyophilized powder | | color | White to Off-White | | CAS DataBase Reference | 2375-03-3(CAS DataBase Reference) |
| Hazard Codes | T | | Risk Statements | 61-40 | | Safety Statements | 53-22-36/37/39-45 | | WGK Germany | 3 | | RTECS | TU4154060 | | Toxicity | LD50 oral in rat: > 5gm/kg |
| 6alpha-Methylprednisolone sodium succinate Usage And Synthesis |
| Uses | 6α-Methylprednisolone 21-Hemisuccinate is a glucocorticosteroid used in anti-inflammatory medication in the treatment of spinal cord injuries. | | Uses | 6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting. | | Brand name | A-Methapred (Abbott);
A-Methapred (Hospira); Solu-Medrol (Pharmacia & Upjohn). | | Biochem/physiol Actions | Glucocorticoid with slightly longer half-life than that of prednisolone. |
| 6alpha-Methylprednisolone sodium succinate Preparation Products And Raw materials |
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