H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT

H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT
  • CAS No.:23815-89-6
Other grades of this product :
H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT Basic information
Product Name:H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT
Synonyms:RPPGF;ARG-PRO-PRO-GLY-PHE;ARG-PRO-PRO-GLY-PHE ACETATE;BRADYKININ (1-5);BRADYKININ FRAGMENT 1-5;H-ARG-PRO-PRO-GLY-PHE-OH TFA;H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT;H-Arg-Pro-Pro-Gly-Phe-OH
CAS:23815-89-6
MF:C27H40N8O6
MW:572.66
EINECS:
Product Categories:Peptide
Mol File:23815-89-6.mol
H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT Chemical Properties
density 1.46±0.1 g/cm3(Predicted)
storage temp. -20°C
pka3.50±0.10(Predicted)
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT Usage And Synthesis
UsesBiologically active fragment of bradykinin
Biochem/physiol ActionsThe bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. It may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for biological activities. BK 1-5 is the minimal peptide that inhibited α-thrombin-induced platelet aggregation and secretion and calcium mobilization. It also prevented α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.
H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT Preparation Products And Raw materials

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