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| H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT Basic information |
| H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT Chemical Properties |
| density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 3.50±0.10(Predicted) |
| H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT Usage And Synthesis |
| Uses | Biologically active fragment of bradykinin | | Biochem/physiol Actions | The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. It may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for biological activities. BK 1-5 is the minimal peptide that inhibited α-thrombin-induced platelet aggregation and secretion and calcium mobilization. It also prevented α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins. |
| H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT Preparation Products And Raw materials |
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