PipaMperone Dihydrochloride

PipaMperone Dihydrochloride
  • CAS No.:2448-68-2
Other grades of this product :
PipaMperone Dihydrochloride Basic information
Product Name:PipaMperone Dihydrochloride
Synonyms:Pipamperone hydrochloride;R4050, 1μ-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4μ-bipiperidine]-4μ-carboxamide dihydrochloride;Nsc170981;Pipamperone DiHCl;Pipamperone dihydrochloride salt;PIPAMPERONE DIHYDROCHLORIDE;carpiperone;floropipamide hydrochloride
CAS:2448-68-2
MF:C21H30FN3O2.2ClH
MW:0
EINECS:2195075
Product Categories:Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:2448-68-2.mol
PipaMperone Dihydrochloride Chemical Properties
Melting point 203-218°C
storage temp. Hygroscopic, Refrigerator, Under Inert Atmosphere
solubility H2O: ~50mg/mL
form powder
color white
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 1
RTECS DW1060000
MSDS Information
PipaMperone Dihydrochloride Usage And Synthesis
Chemical PropertiesOff-White to Pale Yellow Solid
UsesPipamperone dihydrochloride may be used:
  • as an internal standard in liquid chromatography with coulometric detection
  • as an antipsychotic drugs to test its interaction with human ether-a-go-go-related gene (hERG) channel
  • as an internal standard to spike human colostrum samples for reversed phase liquid chromatography- ultraviolet (LC-UV) analysis
UsesAntipsychotic.
DefinitionChEBI: A hydrochloride resulting from the reaction of pipamperone with 2 mol eq. of hydrogen chloride. It is used as an antipsychotic.
Biochem/physiol ActionsPipamperone, a butyrophenone derivative is a pharmacological chaperone and is a membrane-permeable dopamine receptor D4 (DRD4) antagonist. The affinity of pipamperone is higher for DRD4 and 5-hydroxytryptamine 2A receptor (5-HT2A) in comparison with DRD2. It may be useful therapeutic in treating behavioral disorders and psychomotor agitation symptoms.
PipaMperone Dihydrochloride Preparation Products And Raw materials

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