1,2-DIOLEOYL-SN-GLYCEROL

CAS No.：24529-88-2

Other grades of this product :

1,2-DIOLEOYL-SN-GLYCEROL Basic information

Product Name:	1,2-DIOLEOYL-SN-GLYCEROL
Synonyms:	Olein, 1,2-di-, (S)-(-)-;sn-1,2-dioleoylglycerol;1,2-dioleoyl-sn-glycerol (C18:1,(cis)-9);1 2-DIOLEOYL-SN-GLYCEROL AMPOULE;1,2-SN-DIOLEIN;glyceryl 1,2-sn-dioleate;(S)-1,2-Diolein, (S)-Glycerol 1,2-dioleate, 1,2-Di(cis-9-octadecenoyl)-sn-glycerol;(+)-L-Glycerol 1,2-dioleate
CAS:	24529-88-2
MF:	C39H72O5
MW:	620.99
EINECS:
Product Categories:
Mol File:	24529-88-2.mol

1,2-DIOLEOYL-SN-GLYCEROL Chemical Properties

Boiling point	670.8±35.0 °C(Predicted)
density	0.9218 g/cm3
storage temp.	-20°C
pka	13.69±0.10(Predicted)
BRN	1730457

Safety Information

Safety Statements	22-24/25
WGK Germany	3
RTECS	RK1250000
F	23

MSDS Information

Provider	Language
SigmaAldrich	English

1,2-DIOLEOYL-SN-GLYCEROL Usage And Synthesis

Description	1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol and 1,2-dioctanoyl-sn-glycerol are nearly equipotent in induction of the acrosome reaction in human sperm.
Uses	1,2-Dioleoyl-sn-glycerol is an analog of 1,3-Dioleoylglycerol (D4842100 which is used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents.
Uses	18:1 DG may be used: in the lipid-protein overlay screen assay with Arabidopsis Rho-like GTPases recombinant protein and Arabidopsis plasma membrane H+-ATPase in the preparation of the Golgi-like liposomes in giant unilamellar vesicles (GUVs) preparation
Definition	ChEBI: A 1,2-diacyl-sn-glycerol in which the acyl groups at positions 1 and 2 are specified as oleoyl.
General Description	Diacylglycerol/diglyceride (DAG) is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage.
Biochem/physiol Actions	18:1 DG or 1,2-dioleoyl-sn-glycerol (DOG) fails to prevent the late fission events in the Golgi membrane. DOG is used in ferrihaem π–π tetramer aggregate preparation and β-haematin production.

1,2-DIOLEOYL-SN-GLYCEROL Preparation Products And Raw materials

Preparation Products

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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