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| (3S)-3-octanoyloxy-4-trimethylazaniumylbutanoate Basic information |
| (3S)-3-octanoyloxy-4-trimethylazaniumylbutanoate Chemical Properties |
| storage temp. | 2-8°C | | optical activity | [α]/D -17±2°, c = 1 in H2O | | BRN | 5955761 |
| (3S)-3-octanoyloxy-4-trimethylazaniumylbutanoate Usage And Synthesis |
| Uses | Octanoyl-L-carnitine may be used as an analytical standard in the following:- Separation and identification of underivatized octanoyl-L-carnitine in human plasma samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS).
- Quantification of the analyte in biological samples of patients treated with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using high-performance liquid chromatography/tandem quadrupole mass spectrometry (HPLC-TQMS). The feasibility of adding L-carnitine to the peritoneal dialysis (PD) solution in APD-treated end-stage renal disease patients is investigated.
It may be used as a test material for investigating its rate of oxidation by mitochondria, isolated from the livers of fed, starved and glucagon treated virgin and lactating rats. | | Definition | ChEBI: The L-enantiomer of an O-octanoylcarnitine. | | General Description | Octanoyl-L-carnitine is a medium-chain endogenous ester of L-carnitine, obtained via acylcarnitine family transferase. | | Biochem/physiol Actions | L-Octanoylcarnitine is the physiologically active form of octanoylcarnitine and is detected in medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. MCAD is characterized by intolerance to prolonged fasting, recurrent episodes of hypoglycemic coma with medium-chain dicarboxylic aciduria, impaired ketogenesis, and low plasma and tissue carnitine levels. |
| (3S)-3-octanoyloxy-4-trimethylazaniumylbutanoate Preparation Products And Raw materials |
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