Other grades of this product :
| CP 154526 Basic information |
| Product Name: | CP 154526 | | Synonyms: | 7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-butyl-N-ethyl-2,5-diMethyl-7-(2,4,6-triMethylphenyl)-, (Hydrochloride) (1:1);CP-154526 Hydrochloride;N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine monohydrochloride | | CAS: | 257639-98-8 | | MF: | C23H33ClN4 | | MW: | 400.98792 | | EINECS: | | Product Categories: | Amines, Aromatics, Heterocycles, Neurochemicals, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Neurochemicals;Pfizer Compounds;Pharmaceuticals | | Mol File: | 257639-98-8.mol |
| CP 154526 Chemical Properties |
| Melting point | 167-169°C | | storage temp. | 2-8°C | | solubility | DMSO: soluble10mg/mL, clear | | form | powder | | color | white to beige |
| CP 154526 Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid | | Uses | A selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF. It displayed anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant. | | Uses | CP-154526 Hydrochloride is a selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1) (1,2,3). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF and displays anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant. | | Biochem/physiol Actions | CP-154526 is a selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1). |
| CP 154526 Preparation Products And Raw materials |
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