5-Chloro-1-pentyne

CAS No.：14267-92-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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5-Chloro-1-pentyne Basic information

Product Name:	5-Chloro-1-pentyne
Synonyms:	(3-Chloropropyl)acetylene;5-Chloro-1-pentyne,98%;5-chloro-1-E-acetylene;5-Chloro-1-pentyne, 98% 25GR;Chloro-1-pent;Pent-4-yn-1-yl chloride;EOS-60333;5-chloro -1-pentyl
CAS:	14267-92-6
MF:	C5H7Cl
MW:	102.56
EINECS:	238-159-5
Product Categories:	Alkynyl;Halogenated Hydrocarbons;Miscellaneous;Acetylenes;Functionalized Acetylenes;Organic Building Blocks
Mol File:	14267-92-6.mol

5-Chloro-1-pentyne Chemical Properties

Melting point	-61°C (estimate)
Boiling point	67-69 °C145 mm Hg(lit.)
density	0.968 g/mL at 25 °C(lit.)
refractive index	n20/D 1.444(lit.)
Fp	60 °F
storage temp.	2-8°C
form	Liquid
Specific Gravity	0.968
color	Clear colorless to light brown
Water Solubility	Not miscible in water.
BRN	1736710
CAS DataBase Reference	14267-92-6(CAS DataBase Reference)
NIST Chemistry Reference	5-Chloro-1-pentyne(14267-92-6)
EPA Substance Registry System	1-Pentyne, 5-chloro- (14267-92-6)

Safety Information

Hazard Codes	F,Xi
Risk Statements	11-38-36/37/38
Safety Statements	23-24/25-16
RIDADR	UN 1993 3/PG 2
WGK Germany	3
Hazard Note	Irritant
TSCA	Yes
HazardClass	3
PackingGroup	II
HS Code	29032900

MSDS Information

Provider	Language
5-Chloro-1-pentyne	English
ACROS	English
SigmaAldrich	English
ALFA	English

5-Chloro-1-pentyne Usage And Synthesis

Chemical Properties	CLEAR COLOURLESS TO LIGHT BROWN LIQUID
Uses	5-Chloro-1-pentyne is used with α-diazoesters in a copper-catalyzed synthesis of pyrazoles. It is also used in the synthesis of 5-chloro-2-trimethylstannyl-1-pentene by reacting with Me3SnCu.Me2S.
Uses	5-Chloro-1-pentyne was used in the synthesis of 5-chloro-2-trimethylstannyl-1-pentene by reacting with Me₃SnCu.Me₂S. It was also used with α-diazoesters in a copper-catalyzed synthesis of pyrazoles.

5-Chloro-1-pentyne Preparation Products And Raw materials

Preparation Products

1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE-->6-CHLORO-N-HEXANOIC ACID

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