thiocolchicine

thiocolchicine
  • CAS No.:2730-71-4
Other grades of this product :
thiocolchicine Basic information
Product Name:thiocolchicine
Synonyms:thiocolchicine;thiocholchicine;(S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one;(S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one;10-Demethoxy-10-methylthiocolchicine;10-Thiocolchicine;N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide;N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-triMethoxy-10-(Methylthio)-9-oxobenzo[a]heptalen-7-yl]acetaMide
CAS:2730-71-4
MF:C22H25NO5S
MW:415.5
EINECS:220-346-8
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:2730-71-4.mol
thiocolchicine Chemical Properties
Melting point 193℃
alpha D20 -221°
Boiling point 729.1±60.0 °C(Predicted)
density 1.27±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble10mg/mL, clear
pka14.75±0.40(Predicted)
form powder
color white to beige
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
RIDADR UN 1544PSN1 6.1 / PGI
WGK Germany 3
MSDS Information
thiocolchicine Usage And Synthesis
Chemical PropertiesBright Yellow Solid
UsesA muscle relaxant.
Biochem/physiol ActionsThiocolchicine is an antimitotic alkaloid and apoptosis inducer that inhibits tubulin polymerization and microtubule assembly.
thiocolchicine Preparation Products And Raw materials
Raw materialsColchicine-->Thiocolciran-->(R/S)-Colchicine-->Sodium thiomethoxide-->METHYL MERCAPTAN-->Acetic anhydride

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