Other grades of this product :
| Product Name: | ACEA | | Synonyms: | ARACHIDONYL-2'-CHLOROETHYLAMIDE;ARACHIDONYL-2-CHLOROETHYLAMIDE;ARACHIDONOYL 2'-CHLOROETHYLAMIDE;N-(2-CHLOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;ACEA;2'-CHLORO-AEA;Propanamide, 3-chloro-N-(4Z,7Z,10Z,13Z)-4,7,10,13-nonadecatetraen-1-yl- | | CAS: | 273734-07-9 | | MF: | C22H36ClNO | | MW: | 365.98 | | EINECS: | | Product Categories: | | Mol File: | 273734-07-9.mol |
| storage temp. | −20°C | | solubility | DMSO: soluble | | form | oil | | color | pale yellow |
| Enzyme inhibitor | This synthetic CB1 receptor agonist and anandamide (N-
arachidonylethanolamide) analogue (FW = 365.99 g/mol; CAS 220556-69-
4; Symbol: ACEA) is a selective agonist of cannabinoid receptor-1 (Ki =
1.4 nM) but has low affinity to the cannabinoid receptor 2 (Ki = 3.1 μM).
ACEA inhibits forskolin-induced cAMP accumulation in Chinese hamster
ovary cells expressing the human CB1 receptor. It also increases the
binding of [35S]GTPgS to cerebellar membranes and inhibits electrically
evoked contractions of the mouse vas deferens. ACEA produces
hypothermia in mice, an effect that is inhibited by co-administration of the
CB1 receptor antagonist SR141716A. |
| ACEA Preparation Products And Raw materials |
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