Product

4,4'-Difluorobenzhydrylpiperazine

CAS No.：27469-60-9

Other grades of this product :

4,4'-Difluorobenzhydrylpiperazine Basic information

Product Name:	4,4'-Difluorobenzhydrylpiperazine
Synonyms:	1-Bis(4-fluorophenyl)methyl piperazine, >=98%;1-Bis(4-fluorophenyl)methyl Piperzaine;TIMTEC-BB SBB002996;N-[BIS(4-FLUOROPHENYL)METHYL]PIPERAZINE;N-(4,4'-DIFLUOROBENZHYDRYL)PIPERAZINE;1-(4,4'-Difluorobenzhydryl)piperazine 1-(4,4'-Difluorodiphenylmethyl)piperazine;Flunarizine Impurity A;1-BIS (P-FLUOROPHENYL) METHYL PIPERAZINE
CAS:	27469-60-9
MF:	C17H18F2N2
MW:	288.33
EINECS:	248-476-0
Product Categories:	Building Blocks;C16 to C29;Chemical Synthesis;Fluorinated Building Blocks;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;API intermediates;Other Fluorinated Heterocycles;Piperazines
Mol File:	27469-60-9.mol

4,4'-Difluorobenzhydrylpiperazine Chemical Properties

Melting point	88-92 °C(lit.)
Boiling point	130 °C
density	1.1462 (estimate)
vapor pressure	0.001-0.003Pa at 20-25℃
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	soluble in Methanol,Toluene
pka	9.00±0.10(Predicted)
form	Crystalline Powder
color	White to yellow
Water Solubility	0.34 g/L (20 ºC)
BRN	620754
LogP	3.3-3.5 at pH7-11
CAS DataBase Reference	27469-60-9(CAS DataBase Reference)

Safety Information

Hazard Codes	T
Risk Statements	25-36/37/38
Safety Statements	26-45-36/37/39
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
F	10-34
Hazard Note	Toxic
HazardClass	IRRITANT
HazardClass	6.1
PackingGroup	III
HS Code	29335990

MSDS Information

Provider	Language
1-(4,4'-Difluorobenzhydryl)piperazine	English
SigmaAldrich	English
ACROS	English

4,4'-Difluorobenzhydrylpiperazine Usage And Synthesis

Chemical Properties	white to yellow crystalline powder
Uses	1-Bis(4-fluorophenyl)methyl piperazine may be used to synthesize 1-[bis(4-fluorophenyl)methyl]-4-[3-[(N-ethoxycarbonyl-N-phenyl)amino]-2-hydroxypropyl]piperazine and (R, S) 3-[4-(bis(4-fluorophenyl)methyl)piperazin-1-yl]dihydrofuran-2(3H)-one.
General Description	1-Bis(4-fluorophenyl)methyl piperazine is formed during the synthesis of flunarizine. Its crystals exhibits monoclinic crystal system and space group P2₁/c.

4,4'-Difluorobenzhydrylpiperazine Preparation Products And Raw materials

Preparation Products

Flunarizine-->Lomerizine hydrochloride

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