Tilorone dihydrochloride

Tilorone dihydrochloride
  • CAS No.:27591-69-1
Other grades of this product :
Tilorone dihydrochloride Basic information
Product Name:Tilorone dihydrochloride
Synonyms:TILORONE HYDROCHLORIDE;2,7-BIS[2-(DIETHYLAMINO)ETHOXY]-9-FLUORENONE DIHYDROCHLORIDE;TILORONE 2HCL;2,7-Bis-deae-fluorenone;9H-Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-, dihydrochloride;Deae-f;Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-, dihydrochloride;Rmi 10008da
CAS:27591-69-1
MF:C25H36Cl2N2O3
MW:483.47
EINECS:
Product Categories:C15 to C38;Carbonyl Compounds;Chemical Synthesis;Ketones;Organic Building Blocks;strong recommend;Fluorene series;Fused Ring Systems;Building Blocks
Mol File:27591-69-1.mol
Tilorone dihydrochloride Chemical Properties
Melting point 230-233 °C(lit.)
storage temp. Sealed in dry,Room Temperature
solubility Methanol (Slightly)
form Solid
color Orange
Merck 14,9440
InChIKeyBSVYJQAWONIOOU-UHFFFAOYSA-N
CAS DataBase Reference27591-69-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38-40
Safety Statements 7-22-26-37/39
WGK Germany 3
RTECS LL9000000
ToxicityLD50 in mice, rats (single dose): 959, 852 mg/kg orally; 145, 244 mg/kg i.p. (Krueger, Mayer)
MSDS Information
ProviderLanguage
SigmaAldrich English
Tilorone dihydrochloride Usage And Synthesis
DescriptionTilorone is an orally active, antiviral compound that induces interferon production and is reported to have antitumor, anti-inflammatory, and neuroprotective actions. With chronic administration, tilorone induces lysosomal glycosaminoglycan storage, rendering glycosaminoglycans resistant to enzymatic degradation.
Chemical PropertiesOrange-yellow crystalline powder
Usesantiviral
UsesTilorone dihydrochloride is an orally active, interferon-inducing antiviral agent.
UsesTilorone dihydrochloride was used to study the interaction of drugs with synthetic self-complementary DNA by SPR (Surface Plasmon Resonance).
Brand nameTilorone is INN.
General DescriptionEffect of tilorone dihydrochloride on the changes of transmembrane potential of mitochondrial membranes of the isolated rat hepatocytes has been investigated. Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent.
Tilorone dihydrochloride Preparation Products And Raw materials
Raw materials2,7-Dihydroxy-9-fluorenone-->Tilorone-->Diethylamine-->Isopropyl alcohol-->Diethylaminoethanol-->2-Diethylaminoethylchloride hydrochloride

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