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| 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Basic information |
| 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Chemical Properties |
| Melting point | 83-86°C | | Boiling point | 495.7±40.0 °C(Predicted) | | density | 1.347±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO: soluble15mg/mL (clear solution) | | form | powder | | color | white to beige |
| Hazard Codes | Xi | | Risk Statements | 41-43 | | Safety Statements | 26-36/37-39 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 |
| 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid | | Uses | A novel nitric oxide-releasing aspirin, | | Biochem/physiol Actions | NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines. |
| 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Preparation Products And Raw materials |
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![2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID](/img/287118-97-2.jpg "2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID")
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