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| HEXADIMETHRINE BROMIDE Basic information |
| Product Name: | HEXADIMETHRINE BROMIDE | | Synonyms: | SEQUA-BRENE(TM);POLYBRENE;POLY(N,N,N',N'-TETRAMETHYL-N-TRIMETHYLENEHEXAMETHYLENEDIAMMONIUM DIBROMIDE);6,3-ionenebromide;poly((dimethyliminio)hexamethylene(dimethylimino)trimethylenedibromide);HEXADIMETHRIN BROMIDE;HEXADIMETHRINE BROMIDE;Hexadimethrine bromide (Synonyms: 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide) | | CAS: | 28728-55-4 | | MF: | C39H90Br6N6X2 | | MW: | 1122.6 | | EINECS: | | Product Categories: | | Mol File: | 28728-55-4.mol |
| HEXADIMETHRINE BROMIDE Chemical Properties |
| storage temp. | 2-8°C | | solubility | H2O: 0.1 g/mL, clear to slightly hazy, colorless to faintly yellow | | form | gelatinous solid | | Merck | 13,4702 | | CAS DataBase Reference | 28728-55-4 |
| Hazard Codes | Xn | | Risk Statements | 22 | | RIDADR | 2811 | | WGK Germany | 3 | | RTECS | TQ2655000 | | F | 3-10 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | Polymers with mol wt of 5000-10,000 have LD50 i.v. in mice: 25-40 mg/kg (Kimura) |
| HEXADIMETHRINE BROMIDE Usage And Synthesis |
| Uses | Hexadimethrine bromide can be used to transfect mammalian cells with DNA. It can be used to increase the efficiency of lipofection transfections.Hexadimethrine bromide has been used for lentivirus infection in cells. It has been used for infection of cells with retroviral supernatant. | | Uses | Antiheparin agent. A 3mg quantity has been found to enhance peptide degradation in automated sequential analysis. | | Uses | Used as a protein/peptide carrier for protein sequencing. | | General Description | Hexadimethrine bromide is a quaternary ammonium compound which works as a heparin antagonist. It is also involved in the transformation of low molecular weight DNA. | | Purification Methods | Purify it by chromatography on Dowex 50 and/or by filtration through alumina before use [Frank Hoppe-Seyler's Z Physiol Chemie 360 997 1979]. It is hygroscopic, and its solubility in H2O is 10%. |
| HEXADIMETHRINE BROMIDE Preparation Products And Raw materials |
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