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| 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Basic information |
| 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Chemical Properties |
| Melting point | 161-163 °C (lit.) | | Boiling point | 360.05°C (rough estimate) | | density | 1.1825 (rough estimate) | | refractive index | 1.5270 (estimate) | | storage temp. | 2-8°C | | solubility | methanol: soluble | | pka | 4.22±0.30(Predicted) | | form | Crystalline Powder | | color | Off-white to light yellow or light beige | | CAS DataBase Reference | 2882-15-7(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29349990 |
| 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Usage And Synthesis |
| Chemical Properties | slightly yellow fine crystalline powder | | Uses | A metabolite of Indomethacin. | | Uses | - Reactant for preparation of antimalarial agents
- Reactant for preparation of ndomethacin analogs as cyclooxygenase and lipoxygenase inhibitors with antiinflammatory activity
- Reactant for preparation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents
- Reactant for preparation of histone deacetylase inhibitors
- Reactant for preparation of 2,N6,5′-substituted adenosine derivatives as ligands for A2B adenosine receptor
- Reactant for preparation of prostaglandin D2 receptor antagonist
| | Uses | 5-Methoxy-2-methyl-3-indoleacetic acid was used for quantitative determination of indomethacin and its major impurities in suppository and capsule formulations by HPLC. 5-Methoxy-2-methyl-3-indoleacetic acid was used in a study to develop fast, sensitive and simultaneous determination of metabolites of serotonin using liquid chromatography with mass spectrometric detection. | | General Description | 5-Methoxy-2-methyl-3-indoleacetic acid is hydrolysis product of indomethacin. |
| 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Preparation Products And Raw materials |
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