Other grades of this product :
| eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem Basic information |
| eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem Chemical Properties |
| eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem Usage And Synthesis |
| General Description | A cell-permeable and selective inhibitor of the phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF-2α). Shown to offer protection against ER stress-induced apoptosis (EC50 ~15 μM in PC12 cells stimulated with 750 ng/ml of Tunicamycin (Cat. No. 654380). Prevents HSV replication both in Vero cells (IC50 ~3 μM for reducing plaque formation) in vitro and in a mouse cornea infection model in vivo. The solid form of this compound (Cat. No. 324895) is also available. | | Biochem/physiol Actions | Cell permeable: yes |
| eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem Preparation Products And Raw materials |
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