5-METHOXYQUINOLIN-8-AMINE

CAS No.：30465-68-0

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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5-METHOXYQUINOLIN-8-AMINE Basic information

Product Name:	5-METHOXYQUINOLIN-8-AMINE
Synonyms:	8-AMINO-5-METHOXYQUINOLINE;5-METHOXYQUINOLIN-8-AMINE;5-METHOXY-QUINOLIN-8-YLAMINE;8-QuinolinaMine, 5-Methoxy-;8-Amino-5-methoxyquinoline 95%;5-methoxy-8-aminoquinoline;5-methoxy-8-quinolinamine
CAS:	30465-68-0
MF:	C10H10N2O
MW:	174.2
EINECS:
Product Categories:	organic building block
Mol File:	30465-68-0.mol

5-METHOXYQUINOLIN-8-AMINE Chemical Properties

Melting point	90-95°C
Boiling point	355.7±27.0 °C(Predicted)
density	1.217±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
form	powder
pka	3.98±0.12(Predicted)

Safety Information

MSDS Information

5-METHOXYQUINOLIN-8-AMINE Usage And Synthesis

Uses	The Chen auxiliary was reported to be an effective directing group in the synthesis of pyrrolidones from assisting in the activation of C(sp³)-H bonds and can be readily installed through amide bond formation and removed through mild conditions using CAN at room temperature.
General Description	8-Amino-5-methoxyquinoline is a substituted quinoline derivative that can be prepared using 5-chloro-2-nitroaniline as a starting material. It can act as an easily removable directing group and also mediate C-H activation. These properties have been useful for synthesizing isomeric dibenzoxazepinones and complex pyrrolidinones from compounds containing 8-amino-5-methoxyquinoline moiety.

5-METHOXYQUINOLIN-8-AMINE Preparation Products And Raw materials

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