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| HEMICHOLINIUM-3 Basic information |
| Product Name: | HEMICHOLINIUM-3 | | Synonyms: | 2,2’-(1,1’-biphenyl)-4,4’-diylbis(2-hydroxy-4,4-dimethyl-morpholinium)dibrom;2,2’-(4,4’-biphenylylene)bis(2-hydroxy-4,4-dimethyl-morpholiniudibromide;hc-3;hemicholine;hemicholinium-3bromide;hemicholinium-3dibromide;hemicholiniumbromide;hemicholiniumdibromide | | CAS: | 312-45-8 | | MF: | C24H34N2O4.2Br | | MW: | 574.351 | | EINECS: | 206-227-3 | | Product Categories: | | Mol File: | 312-45-8.mol |
| HEMICHOLINIUM-3 Chemical Properties |
| Hazard Codes | T | | Risk Statements | 23/24/25-36/37/38 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 2811 6.1/PG 2 | | WGK Germany | 3 | | RTECS | QF2450000 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | LD50 i.p. in female mice: 0.048-0.082 mg/kg (DiAugustine, Haarstad) |
| HEMICHOLINIUM-3 Usage And Synthesis |
| Uses | Acetylcholine stores depletor | | Uses | Research tool as cholinergic probe, to deplete acetylcholine stores. | | Uses | Hemicholinium-3 has been used in the preparation of Krebs-HC-3 buffer to study its effects on choline uptake and choline acetyltransferase activity in differentiated human neuroblastoma (SK-N-SH) cells. | | Biochem/physiol Actions | Hemicholinium-3 plays a role in blocking the neuronal choline uptake thereby inhibiting acetylcholine synthesis in the brain. |
| HEMICHOLINIUM-3 Preparation Products And Raw materials |
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