N-(2'-(R)-hydroxybehenoyl)-D-erythro-sphingosine

CAS No.：31417-10-4

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
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N-(2'-(R)-hydroxybehenoyl)-D-erythro-sphingosine Basic information

Product Name:	N-(2'-(R)-hydroxybehenoyl)-D-erythro-sphingosine
Synonyms:	N-(2'-(R)-hydroxybehenoyl)-D-erythro-sphingosine;22:0(2R-OH) Ceramide;N-(2'-(R)-HYDROXYBEHENOYL)-D-ERYTHRO-SPHINGOSINE;22:0(2R-OH) CERAMIDE;Docosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2R)-
CAS:	31417-10-4
MF:	C40H79NO4
MW:	638.06
EINECS:
Product Categories:
Mol File:	31417-10-4.mol

N-(2'-(R)-hydroxybehenoyl)-D-erythro-sphingosine Chemical Properties

Boiling point	757.0±60.0 °C(Predicted)
density	0.935±0.06 g/cm3(Predicted)
storage temp.	-20°C
pka	13.26±0.20(Predicted)

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MSDS Information

N-(2'-(R)-hydroxybehenoyl)-D-erythro-sphingosine Usage And Synthesis

General Description	Hydroxy fatty acid (hFA)-sphingolipids are highly found in the myelin sheath. 2-hydroxy fatty acids (hFA) ceramides are present in the surface epithelium of the skin. 22:0(2R-OH) Ceramide is a unique ceramide containing 22C long chain base fatty acid (behenic acid)-with 2′-hydroxyl group in R configuration.
Biochem/physiol Actions	Hydroxy fatty acid (hFA)-sphingolipids play a vital role in cell signaling, cell differentiation and apoptosis. They also help in formation and function of myelin. Ceramides containing hydroxy fatty acid are synthesized by NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H). These hFA-sphingolipids facilitate the epidermal permeability barrier function.

N-(2'-(R)-hydroxybehenoyl)-D-erythro-sphingosine Preparation Products And Raw materials

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