MYCOPHENOLIC ACID GLUCURONIDE

CAS No.：31528-44-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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MYCOPHENOLIC ACID GLUCURONIDE Basic information

Product Name:	MYCOPHENOLIC ACID GLUCURONIDE
Synonyms:	MYCOPHENOLIC ACID GLUCURONIDE;MYCOPHENOLIC ACID B-D-GLUCURONIDE;5-[(2E)-5-Carboxy-3-methyl-2-penten-1-yl]-1,3-dihydro-6-methoxy-7-methyl-3-oxo-4-isobenzofuranyl b-D-Glucopyranosiduronic Acid;Mycophenolic Acid Glucosiduronate;5-[(2E)-5-Carboxy-3-methyl-2-penten-1-yl]-1,3-dihydro-6-methoxy-7-methyl-3-oxo-4-isobenzofuranyl -D-Glucopyranosiduronic Acid;Mycophenolic Acid -D-Glucuronide;Mycophenolic acid-O-beta-D-glucuronide min. 97%;Mycophenolic acid β-D-glucuronide ,98%
CAS:	31528-44-6
MF:	C23H28O12
MW:	496.46
EINECS:
Product Categories:	Aromatics;Glucuronides;Inhibitors;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:	31528-44-6.mol

MYCOPHENOLIC ACID GLUCURONIDE Chemical Properties

Melting point	98-100°C
Boiling point	875.7±65.0 °C(Predicted)
density	1.502±0.06 g/cm3(Predicted)
Fp	2℃
storage temp.	Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility	DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form	Solid
pka	2.76±0.70(Predicted)
color	White to Pale Beige
Stability:	Hygroscopic

Safety Information

Hazard Codes	F,Xn
Risk Statements	11-20/21/22-36
Safety Statements	16-26-36/37
RIDADR	UN 1648 3 / PGII
WGK Germany	2
HS Code	29389090

MSDS Information

MYCOPHENOLIC ACID GLUCURONIDE Usage And Synthesis

Chemical Properties	Off-White Solid
Uses	A metabolite of Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monoph osphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
Uses	A metabolite of Mycophenolic Acid (M831500), an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
General Description	A Certified Spiking Solution^? for use in therapeutic drug monitoring analyses of serum or whole blood by HPLC or LCMS. The glucuronide, also known as MPAG, is the primary metabolite of the immunosuppressant mycophenolic acid and is monitored by clinical labs to ensure patients remain within the drug′s therapeutic range.

MYCOPHENOLIC ACID GLUCURONIDE Preparation Products And Raw materials

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