Product

2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE

CAS No.：316173-57-6

Other grades of this product :

2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE Basic information

Product Name:	2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE
Synonyms:	2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE;SCH 442416;5-Amino-7-(3-(4-methoxyphenyl)propyl)-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine;2-(Furan-2-yl)-7-(3-(4-methoxyphenyl)propyl)-7H-pyrazolo-[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5;7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine,2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-;2-(Furan-2-yl)-7-(3-(4-methoxyphenyl)propyl)-7H-pyrazolo-[4,3-e][1,2,4]triazolo[1,5-c]pyrimidi;2-(Furan-2-yl)-7-(3-(4-methoxyphenyl)propyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine;SCH-442417
CAS:	316173-57-6
MF:	C20H19N7O2
MW:	389.41
EINECS:
Product Categories:
Mol File:	316173-57-6.mol

2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE Chemical Properties

density	1.49±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: ≥20mg/mL
pka	2.77±0.30(Predicted)
form	powder
color	light tan to tan

Safety Information

WGK Germany

MSDS Information

2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE Usage And Synthesis

Uses	SCH 442416 is a potent and selective A2A adenosine receptor antagonist.
Biological Activity	Extremely selective adenosine A 2A receptor antagonist that binds to human and rat A 2A receptors with high affinity (K i values are 0.048 and 0.5 nM respectively). In vitro displays > 23000-fold selectivity for hA 2A over hA 1 and minimal affinity for hA 2B and hA 3 receptors (IC 50 > 10 μ M).
Biochem/physiol Actions	SCH-442416 potent and selective Adenosine A2a antagonist. SCH-442416 is >10,000-fold selective for A2a compared to other adensosine receptors.

2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE Preparation Products And Raw materials

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