rac-Febrifugine Dihydrochloride

rac-Febrifugine Dihydrochloride
  • CAS No.:32434-42-7
Other grades of this product :
rac-Febrifugine Dihydrochloride Basic information
Product Name:rac-Febrifugine Dihydrochloride
Synonyms:rac-Febrifugine Dihydrochloride;3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone dihydrochloride;Febrifugine dihydrochloride;Atensil;ISF-2123;Pildralazine dihydrochloride;Propyldazine hydrochloride
CAS:32434-42-7
MF:C16H19N3O3
MW:301.34036
EINECS:
Product Categories:Aromatics, Intermediates
Mol File:32434-42-7.mol
rac-Febrifugine Dihydrochloride Chemical Properties
Melting point 220-222 °C (decomp)
storage temp. -20°C
solubility H2O: soluble15mg/mL, clear
form powder
color off-white to gray to brown
optical activity[α]/D 10 to 15°, c = 1 in H2O
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
MSDS Information
rac-Febrifugine Dihydrochloride Usage And Synthesis
Chemical PropertiesWhite Solid
Usesrac-Febrifugine dihydrochloride is the salt of Febrifugine, a bioactive constituent of a Chinese medicinal herb that is characterized by its therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases.
Biochem/physiol ActionsFebrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum, the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver toxicity.
rac-Febrifugine Dihydrochloride Preparation Products And Raw materials

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