Product

2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid

CAS No.：32675-71-1

Other grades of this product :

2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Basic information

Product Name:	2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid
Synonyms:	2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid;DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem;1H-Indole-3-propanoic acid, α-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-;(Rac)-RG108
CAS:	32675-71-1
MF:	C19H14N2O4
MW:	334.33
EINECS:
Product Categories:
Mol File:	32675-71-1.mol

2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Chemical Properties

storage temp.	+2C to +8C
form	Yellow solid

Safety Information

MSDS Information

2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Usage And Synthesis

General Description	A cell-permeable, specific DNA methyltransferases inhibitor (IC₅₀ = 115 nM for CpG methylase M.SssI) that displays anti-proliferative, but not cytotoxic, properties. Unlike the commonly used inhibitor 5-azacytidine, RG108 directly interacts with DNA methyltransferase active site via its carboxy group.
Biochem/physiol Actions	Cell permeable: yes

2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Preparation Products And Raw materials

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873