2-NITROCINNAMALDEHYDE

CAS No.：1466-88-2

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2-NITROCINNAMALDEHYDE Basic information

Product Name:	2-NITROCINNAMALDEHYDE
Synonyms:	O-NITROCINNAMALDEHYDE;AKOS BBS-00003259;3-(2-NITROPHENYL)ACRYLALDEHYDE;2'-NITROCINNAMALDEHYDE;2-NITROCINNAMALDEHYDE;2-NITROPHENYLACROLEIN;2-NITROPHENYLACRYLALDEHYDE;2''-NITROCINNAMALDEHYDE 98+%
CAS:	1466-88-2
MF:	C9H7NO3
MW:	177.16
EINECS:	215-988-0
Product Categories:	Aromatic Aldehydes & Derivatives (substituted)
Mol File:	1466-88-2.mol

2-NITROCINNAMALDEHYDE Chemical Properties

Melting point	127-129 °C(lit.)
Boiling point	309.06°C (rough estimate)
density	1.3312 (rough estimate)
refractive index	1.5200 (estimate)
storage temp.	Store below +30°C.
form	Crystals or Powder
color	Light yellow to yellow-brown
Water Solubility	Soluble in methanol. Insoluble in water.
Sensitive	Air Sensitive
BRN	908376
CAS DataBase Reference	1466-88-2(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/38-43
Safety Statements	26-36-36/37
WGK Germany	3
HS Code	29130000

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

2-NITROCINNAMALDEHYDE Usage And Synthesis

Chemical Properties	light yellow to yellow-brown crystals or powder
Uses	It finds its uses as a actinometer for the UV-A range of photostability testing of pharmaceuticals. 2-Nitrocinnamaldehyde can be oxidized to 2-nitrocinnamic acid which can be used in the Baeyer-Emmerling indole synthesis to produce indole and substituted indoles.
Synthesis Reference(s)	Tetrahedron Letters, 31, p. 4497, 1990 DOI: 10.1016/S0040-4039(00)97659-7

2-NITROCINNAMALDEHYDE Preparation Products And Raw materials

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