2-HYDROXY-5-METHYLBENZOPHENONE

CAS No.：1470-57-1

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

2-HYDROXY-5-METHYLBENZOPHENONE Basic information

Product Name:	2-HYDROXY-5-METHYLBENZOPHENONE
Synonyms:	(2-Hydroxy-5-methylphenyl)phenylmethanone;2-Benzoyl-4-methylphenol;5-Methyl-2-hydroxybenzophenone;Benzophenone, 2-hydroxy-5-methyl-;Methanone, (2-hydroxy-5-methylphenyl)phenyl-;RARECHEM FH 1L 0064;2'-HYDROXY 5'-METHYL BENZOPHENONE;2-HYDROXY-5-METHYLBENZOPHENONE
CAS:	1470-57-1
MF:	C14H12O2
MW:	212.24
EINECS:	216-002-1
Product Categories:	C13 to C14;Carbonyl Compounds;Aromatic Benzophenones & Derivatives (substituted);Ketones
Mol File:	1470-57-1.mol

2-HYDROXY-5-METHYLBENZOPHENONE Chemical Properties

Melting point	83-85 °C (lit.)
Boiling point	312.08°C (rough estimate)
density	1.1035 (rough estimate)
refractive index	1.6000 (estimate)
pka	8.24±0.43(Predicted)
form	powder to crystal
color	Light orange to Yellow to Green
CAS DataBase Reference	1470-57-1(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39
WGK Germany	3
Hazard Note	Irritant
HS Code	29145000

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

2-HYDROXY-5-METHYLBENZOPHENONE Usage And Synthesis

Chemical Properties	yellow crystalline powder
Uses	2-?Hydroxy-?5-?methylbenzophenone is a general reagent used in the synthesis of anti-bacterial and anti-fungal agents.
Preparation	Preparation by condensation of benzotrichloride with p-cresol, ? in the presence of aluminium chloride in carbon disulfide for 2 h (75%). The 6,12-diphenyl-2,8-dimethyl-6,12-epoxy-6H,12H-dibenzo[b,f] dioxocin, an intermediate compound, was also formed under these conditions (29%). This “dioxocin”, by hydrolysis with concentrated sulfuric acid at r.t., gave the expected ketone (91%); ? in the presence of aqueous sodium hydroxide in a water bath for 4 h (33%) or in 32–40% aqueous sodium hydroxide at 70–80° (67%).
Synthesis Reference(s)	The Journal of Organic Chemistry, 38, p. 1924, 1973 DOI: 10.1021/jo00950a030

2-HYDROXY-5-METHYLBENZOPHENONE Preparation Products And Raw materials

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873