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| 4-(Methylsulfonyl)phenol Basic information |
| Product Name: | 4-(Methylsulfonyl)phenol | | Synonyms: | 4-(METHYLSULFONYL)PHENOL;4-METHYLSULPHONYLPHENOL;4-METHANESULFONYL-PHENOL;4-(methylsulfonyl)-pheno;4-Hydroxyphenyl methyl sulfone;4-hydroxyphenylmethylsulfone;p-(methylsulfonyl)-pheno;p-(Methylsulfonyl)phenol | | CAS: | 14763-60-1 | | MF: | C7H8O3S | | MW: | 172.2 | | EINECS: | 632-596-9 | | Product Categories: | | Mol File: | 14763-60-1.mol |
| 4-(Methylsulfonyl)phenol Chemical Properties |
| Melting point | 90-95 °C | | Boiling point | 272.52°C (rough estimate) | | density | 1.3692 (rough estimate) | | refractive index | 1.5151 (estimate) | | RTECS | SM1530000 | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO, Methanol | | form | Powder | | pka | pK1:7.83 (25°C) | | color | Tan to pink-brown | | Water Solubility | slight | | BRN | 1866322 | | CAS DataBase Reference | 14763-60-1(CAS DataBase Reference) | | NIST Chemistry Reference | 4-(Methylsulfonyl)phenol(14763-60-1) |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 24/25-26 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29309090 |
| 4-(Methylsulfonyl)phenol Usage And Synthesis |
| Chemical Properties | Tan to pink-brown powder | | Uses | 4-(Methylsulfonyl)phenol is a reagent in the synthesis of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists. Also a reagent in the synthesis of novel 2-(pyridine-2-yl)-1H-benzimidazole derivatives as potent glucokinase activators. | | Reactions | The reaction of 4-(methylsulfonyl)phenol (17.2 g, 100.0 mmol) with p-Toluenesulfonic anhydride as outlined in the general procedure provided 4-(methylsulfonyl)phenyl 4-methylbenzenesulfonate (26.1 g, 81%). |
| 4-(Methylsulfonyl)phenol Preparation Products And Raw materials |
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