N-desferriferrichrome

N-desferriferrichrome
  • CAS No.:34787-28-5
Other grades of this product :
N-desferriferrichrome Basic information
Product Name:N-desferriferrichrome
Synonyms:N-desferriferrichrome;DesferrichroMe;Deferriferrichrome;Ferrichrome Iron-free;deferrichrome;Cyclo(glycylglycylglycyl-N5-acetyl-N5-hydroxy-L-ornithyl-N5-acetyl-N5-hydroxy-L-ornithyl-N5-acetyl-N5-hydroxy-L-ornithyl)
CAS:34787-28-5
MF:C27H45N9O12
MW:687.7
EINECS:
Product Categories:Chelating Agents & Ligands;Intermediates & Fine Chemicals;Pharmaceuticals;Chelating Agents & Ligands, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:34787-28-5.mol
N-desferriferrichrome Chemical Properties
Melting point 197-203°C
storage temp. 2-8°C
solubility DMSO, Methanol
form Solid
color White to Off-White
Safety Information
WGK Germany 3
MSDS Information
N-desferriferrichrome Usage And Synthesis
DescriptionFerrichrome is a hydroxamate siderophore produced by various fungi, including U. sphaerogena, that facilitates iron chelation and uptake by these organisms. It can be utilized as a heterologous siderophore by bacteria, including P. aeruginosa and V. parahaemolyticus. Ferrichrome (0.8 μM) inhibits proliferation of murine spleen mononuclear cells induced by concanavalin A and reduces the number of concanavalin A-stimulated CD4+ T cells expressing the IL-2 receptor. It also inhibits heme-catalyzed oxidation of LDL by hydrogen peroxide in a concentration-dependent manner.
UsesGrowth-promoting iron chelator. Ferrichrome iron-free from Ustilago sphaerogena.
DefinitionChEBI: A homodetic cyclic peptide composed from two units of three glycyl and three N5-acetyl-N5-hydroxy-L-ornithyl residues.
Biochem/physiol ActionsGrowth-promoting iron chelator
N-desferriferrichrome Preparation Products And Raw materials

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