Product

1,3,5[10]-ESTRATRIENE-3,17-DIOL-6-ONE 6-[O-CARBOXYMETHYL]OXIME

CAS No.：35048-47-6

Other grades of this product :

1,3,5[10]-ESTRATRIENE-3,17-DIOL-6-ONE 6-[O-CARBOXYMETHYL]OXIME Basic information

Product Name:	1,3,5[10]-ESTRATRIENE-3,17-DIOL-6-ONE 6-[O-CARBOXYMETHYL]OXIME
Synonyms:	estradiol-6-(o-carboxymethyl)oxime;BETA-ESTRADIOL-6-ONE 6-(O-CARBOXYMETHYLOXIME);6-KETOESTRADIOL 6-(O-CARBOXYMETHYL)OXIME;oestradiol-6-one 6-(O-carboxymethyloxime);β-Estradiol-6-(O-carboxymethyl)oxime, 6-Ketoestradiol 6-(O-carboxymethyloxime), 1,3,5(10)-Estratriene-3,17β-diol-6-one6-(O-carboxymethyloxime), 3,17β-Dihydroxy-1,3,5(10)-estratriene 6-(O-carboxymethyl)oxime;β-Estradiol-6-one 6-(O-carboxymethyloxime);17BETA-ESTRADIOL-6-[O-CARBOXYMETHYL]OXIME;1,3,5[10]-ESTRATRIENE-3,17-DIOL-6-ONE 6-[O-CARBOXYMETHYL]OXIME
CAS:	35048-47-6
MF:	C20H25NO5
MW:	359.42
EINECS:
Product Categories:	Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Mol File:	35048-47-6.mol

1,3,5[10]-ESTRATRIENE-3,17-DIOL-6-ONE 6-[O-CARBOXYMETHYL]OXIME Chemical Properties

Melting point	195-197 °C (decomp)
Boiling point	572.6±60.0 °C(Predicted)
density	1.46±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka	3.10±0.10(Predicted)
form	Solid
color	White to Off-White
BRN	2484202

Safety Information

Safety Statements	22-24/25
WGK Germany	3

MSDS Information

Provider	Language
SigmaAldrich	English

1,3,5[10]-ESTRATRIENE-3,17-DIOL-6-ONE 6-[O-CARBOXYMETHYL]OXIME Usage And Synthesis

Uses	β-Estradiol-6-one 6-(O-carboxymethyloxime) was shown to exhibit regulatory activities towards the expression of leptin, a protein hormone that coordinate appetite/hunger and metabolism.β-Estradiol-6-one 6-(O-carboxymethyloxime) was shown to control the secretion of leptin via membrane associated estrogen receptor alpha in human placental cells.
Definition	ChEBI: A derivative of 17beta-estradiol having an O-(carboxymethyl)oxime group at the 6-position.
General Description	β-Estradiol-6-one 6-(O-carboxymethyloxime) is a derivative of 17β-estradiol.

1,3,5[10]-ESTRATRIENE-3,17-DIOL-6-ONE 6-[O-CARBOXYMETHYL]OXIME Preparation Products And Raw materials

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