1-PalMitoyl-2-arachidoyllecithin

1-PalMitoyl-2-arachidoyllecithin
  • CAS No.:35418-58-7

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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1-PalMitoyl-2-arachidoyllecithin Basic information
Product Name:1-PalMitoyl-2-arachidoyllecithin
Synonyms:1-PalMitoyl-2-arachidoyllecithin;IIZPXYDJLKNOIY-JXPKJXOSSA-N;1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC
CAS:35418-58-7
MF:C44H80NO8P
MW:782.081661
EINECS:
Product Categories:Aliphatics, Glycerols, Fatty Acid Derivatives & Lipids, Inhibitors
Mol File:35418-58-7.mol
1-PalMitoyl-2-arachidoyllecithin Chemical Properties
storage temp. -20°C
Safety Information
Hazard Codes Xn
Risk Statements 63-20-22-36/38-40-48/20/22-67
Safety Statements 26-36/37
RIDADR UN 1888 6.1 / PGIII
WGK Germany 3
MSDS Information
1-PalMitoyl-2-arachidoyllecithin Usage And Synthesis
Description1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells.
Uses1-Palmitoyl-2-arachidoyllecithin, is a phospholipid, that can be used for the studies, and elevation of autoantibodies against oxidized palmitoyl arachidonoyl phosphocholine in patients with hypertension and myocardial infarction.
Uses16:0-20:4 PC is suitable for use:
  • in the preparation of auto-oxidised phospholipid for electrospray ionisation mass spectroscopic (ESI-MS) analysis
  • in liposome preparation for the treatment of organoid
  • as antigen in enzyme linked immunosorbent assay (ELISA) for the detection of autoantibodies to phospholipids
General DescriptionPhosphatidylcholine (PC) is one of the major glycerophospholipids of the eukaryotic membranes. PC is zwitterionic. PC is synthesized via two pathways in higher eukaryotes like the triple methylation of phosphatidylethanolamine and the cytidine diphosphate (CDP)-choline pathway.
Biochem/physiol ActionsPhosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. PC is the dominant phospholipid present in cancer and neo-neoplastic tissues. Level of 16:0-20:4 PC is less in multiple myeloma cells than in normal plasma cells.
1-PalMitoyl-2-arachidoyllecithin Preparation Products And Raw materials

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