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| ASIALOGANGLIOSIDE-GM2 Basic information |
| Product Name: | ASIALOGANGLIOSIDE-GM2 | | Synonyms: | ganglio-n-triaosylceramide;ASIALOGANGLIOSIDE GM2, FROM BOVINE BRAIN;GA2 Ganglioside, Gangliotriosyl ceramide;gangliosides (Gls);CERAMIDE TRIHEXOSIDE;GG3;GANGLIOTRIOSYL CERAMIDE;GA2 GANGLIOSIDE | | CAS: | 35960-33-9 | | MF: | C56H104N2O18 | | MW: | 1093.42756 | | EINECS: | | Product Categories: | | Mol File: | 35960-33-9.mol |
| ASIALOGANGLIOSIDE-GM2 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder |
| ASIALOGANGLIOSIDE-GM2 Usage And Synthesis |
| Description | Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable lengths. [Matreya, LLC. Catalog No. 1512] | | Uses | Ganglioside GM2, Asialo is a semisynthetic ganglioside. | | General Description | Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980. | | Biochem/physiol Actions | Degraded form of Asialoganglioside-GM1 ganglioside. |
| ASIALOGANGLIOSIDE-GM2 Preparation Products And Raw materials |
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