1,2-PHENYLENE PHOSPHOROCHLORIDATE

CAS No.：1499-17-8

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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1,2-PHENYLENE PHOSPHOROCHLORIDATE Basic information

Product Name:	1,2-PHENYLENE PHOSPHOROCHLORIDATE
Synonyms:	3,2-benzodioxaphosphole,2-chloro-2-oxide;o-Phenylenephosphorochloridate;2-CHLORO-1,3,2-BENZODIOXAPHOSPHOLE 2-OXIDE;1,2-PHENYLENE PHOSPHOROCHLORIDATE, TECH.;1,2-PHENYLENE PHOSPHOROCHLORIDATE;1,2-PHENYLENE CHLOROPHOSPHATE;2-Chloro-1,3,2-benzodioxaphosphole 2-oxide, o-Phenylene chlorophosphate;o-Phenylene chlorophosphate
CAS:	1499-17-8
MF:	C6H4ClO3P
MW:	190.52
EINECS:	216-106-7
Product Categories:
Mol File:	1499-17-8.mol

1,2-PHENYLENE PHOSPHOROCHLORIDATE Chemical Properties

Melting point	56-62 °C
Boiling point	120 °C9 mm Hg(lit.)
density	1.57±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
BRN	142368
EPA Substance Registry System	1,3,2-Benzodioxaphosphole, 2-chloro-, 2-oxide (1499-17-8)

Safety Information

Hazard Codes	C
Risk Statements	14-34
Safety Statements	26-36/37/39-45
RIDADR	UN 3261 8/PG 2
WGK Germany	3
F	10
HazardClass	8
PackingGroup	III

MSDS Information

Provider	Language
SigmaAldrich	English

1,2-PHENYLENE PHOSPHOROCHLORIDATE Usage And Synthesis

Uses	Reactant for preparation of: Uridine diphosphate-glucose derivatives as potential chain terminators of β-glucan biosynthesis with antifungal activity Vinyloxy phosphorus monomers Phosphorylation agent
Purification Methods	After distilling it in a vacuum, it sets to a colourless solid. It is soluble in pet ether, *benzene and slightly soluble in Et2O. [Khwaja et al. J Chem Soc (C) 2092 1970, Anschütz & Broeker Justus Liebigs Ann Chem 454 109 1927, Beilstein 6 IV 5602.]

1,2-PHENYLENE PHOSPHOROCHLORIDATE Preparation Products And Raw materials

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