Product

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

CAS No.：36507-30-9

Other grades of this product :

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Basic information

Product Name:	1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
Synonyms:	CARBAMAZEPINE 10,11-EPOXIDE;1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE;1A,10BETA-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE;10,11-epoxycarbamazepine;1a,10b-dihydro-6h-dibenz(b,f)oxiren(d)azepine-6-carboxamide;carbamazepine10,11-oxide;carbamazepineepoxide;10,11-Dihydro-10,11-epoxy-5H-dibenzo[b,f]azepine-5-carboxamide
CAS:	36507-30-9
MF:	C15H12N2O2
MW:	252.27
EINECS:	641-693-5
Product Categories:	Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Aromatics;Heterocycles
Mol File:	36507-30-9.mol

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Chemical Properties

Melting point	204-206°C
Boiling point	390.2±52.0 °C(Predicted)
density	1.377±0.06 g/cm3(Predicted)
Fp	9℃
storage temp.	-20°C
solubility	Chloroform (Slightly), DMSO (Slightly)
pka	13.91±0.20(Predicted)
form	neat
color	White

Safety Information

Hazard Codes	Xn,N,T,F
Risk Statements	22-36/37/38-51/53-39/23/24/25-23/24/25-11
Safety Statements	26-36-61-45-36/37-16-7
RIDADR	2811
WGK Germany	3
RTECS	HQ4430000
HazardClass	6.1(b)
PackingGroup	III

MSDS Information

Provider	Language
SigmaAldrich	English

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Usage And Synthesis

Chemical Properties	White Solid
Uses	A metabolite of Carbamazepine (C175840). Representative lots contained 1-2% carbamazepine by HPLC.
Uses	A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC.
Uses	A metabolite of Carbamazepine. Representative lots contained 1-2% carbamazepine by HPLC
Definition	ChEBI: An epoxide and metabolite of carbamazepine.
General Description	Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine.
Biochem/physiol Actions	First metabolite of carbamazepine

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Preparation Products And Raw materials

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