Other grades of this product :
| MST-312 Basic information |
| Product Name: | MST-312 | | Synonyms: | Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem;TELOMERASE INHIBITOR IX;MST-312;N,N'-BIS(2,3-DIHYDROXYBENZOYL)-1,3-PHENYLENEDIAMINE;N,N′-1,3-Phenylenebis-[2,3-dihydroxy-benzamide];N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide;Benzamide, N,N'-1,3-phenylenebis[2,3-dihydroxy-;MST-312 >=98% (HPLC) | | CAS: | 368449-04-1 | | MF: | C20H16N2O6 | | MW: | 380.35 | | EINECS: | | Product Categories: | | Mol File: | 368449-04-1.mol |
| MST-312 Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: ≥20mg/mL | | form | White solid | | color | off-white to light tan |
| Hazard Codes | N | | Risk Statements | 50 | | Safety Statements | 61 | | WGK Germany | 2 |
| MST-312 Usage And Synthesis |
| Uses | MST-312 has been used in cell invasion assay using mouse fibroblast cells (NIH-3T3) and in the co-immunoprecipitation experiments in colon fibroblast. | | General Description | A cell-permeable, bis-catechol containing, m-phenylenediamide compound that displays anti-proliferative properties. Acts as a potent, reversible inhibitor of telomerase activity (IC50 = 670 nM, TRAP lysate prepared from U937 cells). Prolonged treatment with MST-312 has been reported to result in telomere shortening and growth arrest in U937 cells. Does not inhibit the activity of Taq DNA polymerase (IC50 >3 μM). | | Biochem/physiol Actions | Cell permeable: yes |
| MST-312 Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye