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| ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Basic information |
| Product Name: | ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate | | Synonyms: | O-Ethyl-DOPA;TV-1203;ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate;L-DOPA Ethyl Ester;2(S)-Amino-3-(3,4-dihydroxyphenyl)propionic acid ethyl ester;3,4-Dihydroxy-L-phenylalanine ethyl ester;3-Hydroxy-L-tyrosine ethyl ester;L-Dopa-Et | | CAS: | 37178-37-3 | | MF: | C11H15NO4 | | MW: | 225.24 | | EINECS: | | Product Categories: | | Mol File: | 37178-37-3.mol |
| ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Chemical Properties |
| Boiling point | 394.2±37.0 °C(Predicted) | | density | 1.278±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | H2O: ≥12mg/mL at warmed to 60°C | | pka | 9.67±0.20(Predicted) | | form | powder | | color | white to tan |
| Hazard Codes | Xn | | Risk Statements | 22-36 | | Safety Statements | 26 | | WGK Germany | 3 |
| ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Usage And Synthesis |
| Uses | Antiparkisonian. | | Uses | L-Dopa ethyl ester has been used to study the protective effects of piperlongumine (PLG) on rotenone-induced Parkinson disease (PD). | | Biochem/physiol Actions | L-Dopa ethyl ester is a prodrug of levodopa that has greater gastric solubility. The drug is rapidly hydrolyzed to levodopa by nonspecific esterases in the gastrointestinal tract. L-Dopa ethyl ester (etilevodopa)-carbidopa treatment was well tolerated but did not demonstrate better efficacy compared with standard levodopa-carbidopa treatment. L-Dopa ethyl ester should have a significant brain penetration following an administration by injection. |
| ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Preparation Products And Raw materials |
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