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| 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE Basic information |
| Product Name: | 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE | | Synonyms: | 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE;CHOLOYLGLYCINE HYDROLASE FROM CLOSTRIDIUM PERFINGENS (C. WELCHII);3α,7α,12α-trihydroxy-5β-cholan-24-oylglycine amidohydrolase;choloylglycine hydrolase from clostridium perfringens (c. welchii);EC 3.5.1.24;CHOLOYLGLYCINE HYDROLASE;Native Clostridium perfringens (C. welchii) Choloylglycine Hydrolase;Choloylglycine Hydrolase from Clostridium perfringens (C.?welchii) lyophilized powder, >=100 units/mg protein | | CAS: | 37289-07-9 | | MF: | | MW: | 0 | | EINECS: | | Product Categories: | | Mol File: | Mol File |
| 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder |
| 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE Usage And Synthesis |
| Uses | The enzyme from Sigma has been used in the analysis of bile samples in various studies. | | Biochem/physiol Actions | The enzyme is an N-terminal nucleophilic (Ntn) hydrolase that catalyzes the hydrolysis of amide bonds, liberates the glycine/taurine moiety from the steroid core and eventually yields unconjugated bile acids. Agents that oxidize thiol groups (e.g., p-mercuribenzoate, iodoacetamide, Hg2+, Cu2+, and Cd2+) have been shown to strongly inhibit bile salt hydrolase (BSH) activity in Clostridium perfringens. |
| 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE Preparation Products And Raw materials |
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