Other grades of this product :
| [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Basic information |
| Product Name: | [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid | | Synonyms: | [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid;2-(7-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-2-oxo-2H-chroMen-4-yl)acetic acid;7-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-2H-1-benzopyran-4-acetic acid;7-N-Fmoc-aminocoumarin-4-acetic acid;2-[7-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-2-oxo-1-benzopyran-4-yl]acetic acid;2H-1-Benzopyran-4-acetic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-;Fmoc-7-aminocoumarin-4-acetic acid;N-Fmoc-Aminocoumarin-4-acetic acid | | CAS: | 378247-75-7 | | MF: | C26H19NO6 | | MW: | 441.43 | | EINECS: | | Product Categories: | | Mol File: | 378247-75-7.mol |
| [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Chemical Properties |
| storage temp. | Store at +2°C to +8°C. |
| [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Usage And Synthesis |
| General Description | Fmoc-ACA-OH is a useful tool for the SPPS of AMC fluorogenic protease substrates. Fmoc-ACA-OH [1] must be first loaded onto a Wang-type resin. Any unreacted linker hydroxyls must be capped using acetic anhydride. Following Fmoc removal, the first amino acid should be coupled withy HATU/collidine [2]. Insertion of ACA into the middle of a peptide provides fluorogenic substrates for endopeptidases [3]. Treatment of the ACC peptide obtained after TFA cleavage with aqueous base causes facile decarboxylation and formation of the AMC peptide. |
| [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Preparation Products And Raw materials |
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![[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid](/img/378247-75-7.jpg "[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid")
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