Product

N-palMitoyl-1-deoxysphinganine (M18:0/16:0)

CAS No.：378755-69-2

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N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Basic information

Product Name:	N-palMitoyl-1-deoxysphinganine (M18:0/16:0)
Synonyms:	N-palMitoyl-1-deoxysphinganine (M18:0/16:0);N-C16-deoxysphinganine;N-PALMITOYL-1-DEOXYSPHINGANINE (M18:0/16:0);N-C16-DEOXYSPHINGANINE;Hexadecanamide, N-[(1S,2R)-2-hydroxy-1-methylheptadecyl]-
CAS:	378755-69-2
MF:	C34H69NO2
MW:	523.92
EINECS:
Product Categories:
Mol File:	378755-69-2.mol

N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Chemical Properties

Boiling point	635.5±38.0 °C(Predicted)
density	0.882±0.06 g/cm3(Predicted)
storage temp.	-20°C
pka	14.54±0.20(Predicted)

Safety Information

MSDS Information

N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Usage And Synthesis

General Description	N-C16-deoxysphinganine Commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. The N-acyl group can be 16, 20 and 24 carbon chain. N-acylsphinganines (dihydroceramides) are synthesized by the acylation of sphingoid bases in the presence of ceramide synthases (CerS).
Biochem/physiol Actions	N-acylsphinganines (dihydroceramides) levels are lower during ceramide synthase inhibition. They are intermediates of ceramide and dihydrosphingolipids synthesis. Treatment of MCF7 cancer cells with fenretinide alters sphingolipid metabolism.

N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Preparation Products And Raw materials

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