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| N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE Basic information |
| Product Name: | N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE | | Synonyms: | N-BUTYL-N-(4-HYDROXYBUTYL)NITROSAMIN;N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE;N-BUTYL-N-(4-HYDROXYBUTYL)NITROSAMINE;N-BUTYL-N-NITROSO-4-AMINOBUTANOL;N-BUTYL-N-BUTAN-4-OL-NITROSAMINE;N-BUTYL-N-BUTANOLNITROSAMINE;1-Butanol, 4-(butylnitrosamino)-;4-(1-Butyl-2-oxohydrazino)-1-butanol | | CAS: | 3817-11-6 | | MF: | C8H18N2O2 | | MW: | 174.24 | | EINECS: | 625-015-5 | | Product Categories: | | Mol File: | 3817-11-6.mol |
| N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE Chemical Properties |
| Boiling point | 167 °C / 5mmHg | | density | 1.01 | | refractive index | 1.4700-1.4740 | | Fp | 147 °C | | storage temp. | 2-8°C | | form | clear liquid | | color | Light yellow to Amber to Dark green | | Stability: | Stability | | EPA Substance Registry System | 4-(Butylnitrosoamino)butanol (3817-11-6) |
| Hazard Codes | T | | Risk Statements | 45-22 | | Safety Statements | 53 | | WGK Germany | 3 | | RTECS | EL1225000 |
| N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE Usage And Synthesis |
| Chemical Properties | red liquid | | Uses | N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN), a carcinogen, is used to induce histiologically relevant aggressive urinary bladder cancer in animal models. | | Definition | ChEBI: A nitrosamine that has butyl and 4-hydroxybutyl substituents. In mice, it causes high-grade, invasive cancers in the urinary bladder, but not in any other tissues. | | General Description | Dark red liquid. | | Air & Water Reactions | Water soluble. | | Reactivity Profile | A hydroxylated and nitrated amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. | | Biochem/physiol Actions | Carcinogen used to induce urinary bladder cancer in animal models. The result of exposure is histologically comparable to human urinary bladder tumorigenesis. Used in chemopreventative studies. |
| N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE Preparation Products And Raw materials |
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